About this course

Learning Objectives

• Learners will be able to describe the key clinical features of Persistent Demand Avoidance.
• Learners will be able to evaluate the advantages and disadvantages of using Persistent Demand Avoidance as a diagnostic entity.
• Learners will be able to analyze the types of data that would be needed to classify Persistent Demand Avoidance as a diagnostic entity.

Learning Levels

• Beginner

Target Audience

Course Instructor(s)

• 

  Daniel Pine, MD

  Psychiatrist

  Practice Philosophy: Daniel S. Pine, MD, is a psychiatrist specializing in the treatment of anxiety and mood disorders in children and adolescents. He is widely acknowledged as one of the world’s top anxiety researchers, and applies his extensive knowledge through diagnosis and treatment of young patients at The Ross Center. Families value the clinical expertise he provides through psychiatric assessment of mood, anxiety, and behavioral disorders, and his medical acumen in prescribing medications that take into consideration a child’s age, diagnosis, symptom duration and severity. He is often sought out by parents and families for clinical consultations in more complex cases, and can provide second opinions diagnostically for those who have struggled for answers. When appropriate, he collaborates with a child’s therapist and other providers to help insure consistent delivery of care. Families appreciate his sensitivity and compassion, and benefit from his vast understanding of the biology behind the mind of an anxious child.

  Areas of Expertise: Dr. Pine is a renowned expert in the field of pediatric mental health. His background in research has led to greater understanding of the biological roots of psychiatric disorders. He is a leader in the development of diagnostic tools and treatments for childhood psychiatric disorders. As a clinician, he uses this wealth of experience to successfully treat anxiety, mood, and behavioral disorders in children and adolescents.

  Experience and Training: Dr. Pine also serves at the National Institute of Mental Health (NIMH) as the Chief Psychiatrist, Section on Development and Affective Neuroscience, in the Intramural Research Program. He received his medical degree from the University of Chicago, and spent 10 years at Columbia University’s College of Physicians and Surgeons in training and research on child psychiatry. His research has focused on the epidemiology, biology, and treatment of pediatric mental illnesses, and is featured in over 500 published scientific papers. Additionally, Dr. Pine has chaired the Food and Drug Administration’s Psychopharmacology Drug Advisory Board. His many honors include the Blanche Ittelson Award from the American Psychiatric Association for outstanding research contributions to the field of child psychiatry.

Disclosure

References

• Deng, Z.-D., Luber, B., Balderston, N. L., Velez Afanador, M., Noh, M. M., Thomas, J., Altekruse, W. C., Exley, S. L., Awasthi, S., & Lisanby, S. H. (2020). Device-based modulation of Neurocircuits as a therapeutic for psychiatric disorders. Annual Review of Pharmacology and Toxicology, 60(1), 591–614. https://doi.org/10.1146/annurev-pharmtox-010919-023253
• Hyde, J., Carr, H., Kelley, N., Seneviratne, R., Reed, C., Parlatini, V., Garner, M., Solmi, M., Rosson, S., Cortese, S., & Brandt, V. (2022). Efficacy of neurostimulation across mental disorders: Systematic review and meta-analysis of 208 randomized controlled trials. Molecular Psychiatry, 27(6), 2709–2719. https://doi.org/10.1038/s41380-022-01524-8
• Kan, R. L., Padberg, F., Giron, C. G., Lin, T. T., Zhang, B. B., Brunoni, A. R., & Kranz, G. S. (2023). Effects of repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex on symptom domains in neuropsychiatric disorders: A systematic review and cross-diagnostic meta-analysis. The Lancet Psychiatry, 10(4), 252–259. https://doi.org/10.1016/s2215-0366(23)00026-3
• Papakostas, G. I., Trivedi, M. H., Shelton, R. C., Iosifescu, D. V., Thase, M. E., Jha, M. K., Mathew, S. J., DeBattista, C., Dokucu, M. E., Brawman-Mintzer, O., Currier, G. W., McCall, W. V., Modirrousta, M., Macaluso, M., Bystritsky, A., Rodriguez, F. V., Nelson, E. B., Yeung, A. S., Feeney, A., … Fava, M. (2024). Comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment resistant depression (ascertain-TRD) a randomized clinical trial. Molecular Psychiatry, 29(8), 2287–2295. https://doi.org/10.1038/s41380-024-02468-x
• Sabé, M., Hyde, J., Cramer, C., Eberhard, A., Crippa, A., Brunoni, A. R., Aleman, A., Kaiser, S., Baldwin, D. S., Garner, M., Sentissi, O., Fiedorowicz, J. G., Brandt, V., Cortese, S., & Solmi, M. (2024). Transcranial magnetic stimulation and transcranial direct current stimulation across mental disorders. JAMA Network Open, 7(5). https://doi.org/10.1001/jamanetworkopen.2024.12616